Menopausal Symptoms

Symptoms Treatable by Hormone Therapy

The most common symptom of menopause and easiest to recognize, is the hot flash (a sudden wave of heat and sweat). The following symptoms, when moderate to severe, are treatable by hormone therapy:1

  • Hot flashes
  • Night sweats and associated sleep disturbances
  • Dryness, itching and burning in and around the vagina


If you use hormone therapy only to treat dryness, itching, and burning in and around your vagina, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.

Postmenopausal Osteoporosis

CombiPatch is not indicated for the treatment of postmenopausal osteoporosis. Osteoporosis, thinning of the bones, is a major health concern after menopause. Women receiving no estrogen lose about 20% of their total body calcium during the first 10 years after menopause. In addition to hormone therapy (HT), weight-bearing exercise and a diet high in calcium and vitamin D can help.

If you use hormone therapy only to prevent osteoporosis from menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.

Mood Changes

CombiPatch is not indicated for the treatment of mood changes. Menopausal symptoms such as hot flashes may interrupt your sleep, causing tiredness and possibly mood changes. However, mood changes can also be caused by non-hormone related issues. So it’s important to explore all possible causes with your doctor.


WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT COMBIPATCH (A COMBINATION OF ESTROGEN AND PROGESTIN HORMONES)?

Do not use estrogens and progestins to prevent heart disease, heart attacks, strokes or dementia (decline in memory and thinking skills). Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots, and may increase your risk of dementia.

Do not use CombiPatch if you have had your uterus removed (hysterectomy). CombiPatch should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.

The most common side effects that may occur with CombiPatch are breast pain, vaginal bleeding, and headache.

CombiPatch is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; and treat certain conditions in which a young woman’s ovaries do not produce enough estrogens naturally. If you use CombiPatch only to treat your dryness, itching and burning in or around the vagina, talk with your health care professional about whether a topical vaginal product would be better for you.

You and your health care professional should talk regularly about whether you still need treatment with CombiPatch and whether you are taking the lowest dose that works for you.

*CombiPatch® is not indicated for the prevention of postmenopausal osteoporosis.

The information contained within this web site is appropriate for U.S. residents only. A visit to this site should not replace a visit to your doctor.

Available by prescription only.

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