How It Works

CombiPatch is an alcohol-free patch with three layers that release the correct amount of each hormone. It releases both estrogen and progestin continuously through your skin.

DOT Matrix™ Technology

CombiPatch was created using the patented DOT Matrix delivery system. DOT Matrix technology allows CombiPatch to be the smallest combination HT patch available that can help treat moderate to severe menopausal symptoms1 effectively. Despite being so small, CombiPatch provides controlled, sustained release of hormones directly through your skin and into your bloodstream over 3 ½ days.

Effective Levels of Hormones

The levels of hormones in the blood from CombiPatch are similar to levels during your menstrual cycle.

Source of Hormones

For women who are interested in the source of the hormones in their therapy, the estrogen and progestin in CombiPatch (estradiol and norethindrone acetate) are chemically synthesized from plant sources. This does not mean that CombiPatch is safer or more effective than other hormone therapies.

Convenient

CombiPatch has two types of hormones in one single patch. And you only have to change it twice a week. It’s easy and only takes about 10 seconds to apply.


Learn how to apply CombiPatch.


WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT COMBIPATCH (A COMBINATION OF ESTROGEN AND PROGESTIN HORMONES)?

Do not use estrogens and progestins to prevent heart disease, heart attacks, strokes or dementia (decline in memory and thinking skills). Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots, and may increase your risk of dementia.

Do not use CombiPatch if you have had your uterus removed (hysterectomy). CombiPatch should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.

The most common side effects that may occur with CombiPatch are breast pain, vaginal bleeding, and headache.

1CombiPatch is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; and treat certain conditions in which a young woman’s ovaries do not produce enough estrogens naturally. If you use CombiPatch only to treat your dryness, itching and burning in or around the vagina, talk with your health care professional about whether a topical vaginal product would be better for you.

You and your health care professional should talk regularly about whether you still need treatment with CombiPatch and whether you are taking the lowest dose that works for you.

DOT Matrix™ is a trademark of Noven Pharmaceuticals, Inc.

The information contained within this web site is appropriate for U.S. residents only. A visit to this site should not replace a visit to your doctor.

Available by prescription only.

Copyright © 2006 Novogyne Pharmaceuticals. All rights reserved.